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Premature ejaculation (PE) is a common sexual health issue affecting many men worldwide. While prescription medications like Duratia 30, which contains Dapoxetine, are widely used for its treatment, there are also several over-the-counter (OTC) remedies available. This article will compare Duratia 30 to OTC options for premature ejaculation, highlighting their effectiveness, safety, and benefits. 1. Active Ingredients and Mechanism of Action Duratia 30: Duratia 30 contains Dapoxetine, a selective serotonin reuptake inhibitor (SSRI) that is specifically designed to treat premature ejaculation. Dapoxetine works by increasing serotonin levels in the brain, which helps delay ejaculation and improves control during sexual activity. It’s fast-acting, usually taken 1-3 hours before intercourse, and is specifically approved for PE, making it a targeted treatment for this condition. Over-the-Counter Remedies: OTC remedies for premature ejaculation typically include products like topical numbing creams, sprays, or herbal supplements. Common OTC options include: Topical creams or sprays: These usually contain local anesthetics such as lidocaine or benzocaine, which reduce sensitivity in the penis and delay ejaculation. These products are applied directly before sexual activity. Herbal supplements: These may contain natural ingredients such as ginseng, tribulus terrestris, ashwagandha, and other herbs believed to support sexual function. However, the scientific evidence supporting their effectiveness for PE is often limited. 2. Effectiveness Duratia 30: Duratia 30 is a clinically proven treatment for premature ejaculation. Studies show that Dapoxetine is effective in prolonging the time before ejaculation, allowing men to have better control during sex. It has been shown to increase the intravaginal ejaculatory latency time (IELT), which is the time taken to ejaculate during intercourse, significantly in many patients. The effectiveness of Duratia 30 is consistent due to its targeted action on serotonin receptors.